Brian Chan

Merkle Lab (basement)
University Park
PA 16802, USA

Tel. +1 814 867 4191
thebrianchan@gmail.com
http://www.thereadgroup.net


Research interest


Degrees

BSc (Hons) Parasitology, University of Glasgow (1990-1993).

HND in Biological Sciences, Napier College, Edinburgh (1987-1990).


Research experience

Pennsylvania State University (2008-current).
Senior Research Assistant

University of Edinburgh (1996-2008).
Post-Graduate Research Associate

The Royal Veterinary College, University of London (1993-1996).
Research technician

BS&S (Scotland) Ltd, Edinburgh (summer 1988).
Histopathology Lab technician


Publications

Schneider, P., Chan, B.H.K., Reece, S.E., & Read, A.F. (2008). Does the drug sensitivity of malaria parasites depend on their virulence? Malaria Journal. 7:257. 

Barclay, V.C., Chan, B.H.K., Anders, R.F., & Read, A.F. (2008). Mixed allele malaria vaccines: host protection and within-host selection. Vaccine. 26: 6099-6107.

Mideo, N., Barclay, V.C., Chan, B.H.K., Savill, N.J., Read, A.F., & Day, T. (2008). Understanding and predicting strain-specific patterns of pathogenesis in the rodent malaria, Plasmodium chabaudi. American Naturalist. 172: E214-E238. 

Grech, K., Chan, B.H.K., Anders, R.F & Read, A.F. (2008). The impact of immunization on competition with Plasmodium infections. Evolution. 62: 2359-2371. 

Long, G.H., Chan. B.H.K., Allen, J.E., Read, A.F., & Graham, A.L. (2008). Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites. BMC Evolutionary Biology. 

Barclay, V.C., Råberg, L., Chan, B.H.K., Brown, S., Gray, D. & Read, A.F. (2008). CD4+ T cells do not mediate within-host competition between genetically diverse malaria parasite. Proceedings of the Royal Society of London Series B. 275: 1171-1179. 

Long, G.H., Chan. B.H.K., Allen, J.E., Read, A.F., & Graham, A.L. (2008). Blockade of TNF receptor 1 reduces disease severity but increase parasite transmission during Plasmodium chabaudi chabaudi infection. International Journal for Parasitology. (Available on line). 

Long, G. H., Chan, B.H.K., Allen, J.E., Read, A.F. & Graham, A.L. (2006). Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections. Parasitology. 133 (6):673-684. 

Wargo, A., Randle, N., Chan, B.H.K., Thompson, J., Read, A.F., & Babiker, H.A. (2006). Plasmodium chabaudi: reverse transcription PCR (RT-PCR) for the detection and quantification of transmission stage malaria parasites. Experimental Parasitology. 112: 13-20. 

Blanford, S., Chan, B.H.K., Jenkins, N., Sim, D., Turner, R.J., Read, A.F., & Thomas, M.B. (2005) Fungal pathogen reduces potential for malaria transmission. Science. 308: 1638-1641. 

de Roode, J.C., Pansini, R., Cheesman, S.J., Helinski, M.E.H., Huijben, S., Wargo, A.R., Bell, A.S., Chan, B.H.K ., Walliker, D., & Read, A.F. (2005). Virulence and competitive ability in genetically diverse malaria infections. Proceedings of the National Academy of Sciences USA.102: 7624-7628.

de Roode, J.C., Read, A.F., Chan, B.H.K., & Mackinnon, M.J (2003.) Rodent malaria parasites suffer from the presence of conspecific clones in three-clone Plasmodium chabaudi infections. Parasitology 127 (5):411-418. 

Guinnee, M.A., Gemmill, A.W., Chan, B.H.K., Viney, M.E., & Read, A.F (2003). Host immune status affects maturation time in two nematode species-but not as predicted by a simple life history model. Parasitology 127 (5): 507-512. 

Ferguson, H.M., Mackinnon, M.J,. Chan, B.H.K., & Read, A.F (2003). Mosquito mortality and the evolution of malaria virulence. Evolution 57 (12): 2792-2804. 

Timms, B., Colegrave, N., Chan, B.H.K., & Read, A.F. (2001). The effect of parasite dose on severity of disease in the rodent malaria Plasmodium chabaudi. Parasitology 123: 1-11. 


Miscellaneous

Interests

Martial arts: Karate, ju jitsu, judo, Brazilian jiu jitsu and Self defence strategies

Racket sports: squash, tennis, badminton.

Volleyball, Cycling, Photography ,Cooking, Dog walking